Report Overview

Global Orthobiologics Market- Industry Trends & Forecast Report 2028

The global orthobiologics market was worth USD 6.2 billion in 2021 and is further projected to reach USD 8.8 billion by the year 2028, growing at a CAGR of 5.20% during the forecast period. The global orthobiologics market is flourishing at a high rate owing to the increasing prevalence of broken bones and injured muscles, tendons, and ligaments due to changing lifestyles and the increasing rate of road and other types of accidents. The rising adoption of orthobiologics among athletes is also driving the growth of the market.

Orthobiologics - Overview

Orthobiologics are biological substances that are used to help injuries heal more quickly. These substances are often made from products that are naturally found in the body. Orthobiologics helps in boosting the healing process of injuries. This kind of procedure plays an important role in avoiding invasive treatment methods. These substances are injected into the affected areas in higher concentrations to help with the treatment.

Orthobiologics Market Forecast and Trends

Growth Drivers

Increasing Rate of Road and Other Accidents

The concerning surge in the rate of road and other types of accidents that physically affects the body is emerging as the major driving factor for the global orthobiologics market. According to a report by the World Health Organization, around 20 to 50 million people suffer from non-fatal and fatal injuries during a road traffic crash every year. Due to this, the demand in the global orthobiologics market is surging for effective and faster treatment.

Extensive Research and Development Activities

With the expanding scope of the global orthobiologics market, the research institutes and pharmaceutical industry are significantly investing and focusing on R&D activities in this field. The research conducted is mainly focused on developing new products and expanding the application of the orthobiologics market. Several studies are also undergoing in this field. For instance, Sanford Health is conducting research to study the potential of orthobiologics and regenerative medicine for people with osteoarthritis.

Restraints

High Cost of Orthobiologics

The high cost of orthobiologics acts as a major restraining factor for the growth of the market. According to a report by the Foundation for Orthopedic Research and Education (FORE), the cost of two orthobiologics, platelet-rich pharma injections, and stem cell injections ranges from around a few hundred dollars to as much as USD 12,000 per treatment. Therefore, orthobiologics treatment is still concentrated among western countries with the development of healthcare infrastructure and high disposable income groups.

Orthobiologics Market - By Product

Based on product, the global orthobiologics market is segmented into viscosupplementation products, demineralized bone matrices, synthetic orthobiologics, bone morphogenic protein, allografts, plasma-rich protein, and bone marrow aspirate concentrate. The viscosupplementation products hold the largest share in the market. On account for a wide range of goods available and their unparalleled popularity in conditions like osteoarthritis and hip degenerative joint disease, these products have a high adoption rate.

Orthobiologics Market - By Application

Based on application, the global orthobiologics market is segmented into osteoarthritis and degenerative arthritis, spinal fusion, soft-tissue injuries, fracture recovery, and maxillofacial and dental applications. Spinal fusion accounts for the largest market share because of its potential to give high bone stability and rapid bone healing, consistent penetration of demineralized bone matrices, bone morphogenetic proteins, autografts, and allografts in spinal fusion procedures has been found to improve long-term spinal problems.

Orthobiologics Market - Regional Insights

Geographically, the global orthobiologics market is segmented into North America, Europe, Asia-Pacific, Latin America, Middle East & Africa. North America dominates the orthobiologics market owing to the developed healthcare infrastructure and high adoption of advanced treatment methods in healthcare facilities. Furthermore, the presence of leading industry players and favorable reimbursement policies also play a crucial role in driving market growth. However, the Asia-Pacific region is projected to witness the highest growth rate during the forecast period.

Competitive Landscape

The leading market players of the global orthobiologics market are Arthrex Inc., Seaspine Holdings Corporation, Sanofi, Bone Support, DePuy Synthes, Integra Lifesciences, Globus Medical Inc., NuVasive Inc., Terumo Corporation, Medtronic PLC, Stryker Corporation, Zimmer Biomet, Pioneer Surgical Technology, Smith & Nephew plc, Bioventus LLC, Orthofix, Inc., Genzyme, Bone Biologics, Corp., Osiris Therapeutics, Inc., and other prominent players.

The market is highly competitive with the presence of several multinational corporations and industrial giants. These companies significantly invest in research and development activities to introduce innovations into their offerings and are constantly launching new products. The adoption of competitive strategies such as partnerships, mergers, acquisitions, collaborations, etc., is also prominent in this market.

Recent Development

• In March 2022, SeaSpine Holding, a US-based advanced spinal cord technologies company, announced the launch of new orthobiologic products; NorthStar cervical facet fusion and Flash navigation lumbar facet fusion.

• In August 2021, Bioventus, a US-based orthobiologics company, announced the acquisition of CartiHeal, an Israeli medical tech company.

Scope of the Report

By Product

• Viscosupplementation Products

• Demineralized Bone Matrices

• Synthetic Orthobiologics

• Bone Morphogenic Protein

• Allografts

• Plasma-Rich Protein

• Bone Marrow Aspirate Concentrate

By Application

• Osteoarthritis and Degenerative Arthritis

• Spinal Fusion

• Soft-Tissue Injuries

• Fracture Recovery

• Maxillofacial and Dental Applications

By End User

• Hospitals, Orthopedic Clinics, & Ambulatory Care Centers

• Research & Academic Institutes

• Dental Clinics and Facilities

By Region

• North America

• Europe

• Asia-Pacific (APAC)

• Latin America (LATAM)

• Middle East & Africa (MEA)

1. Research Framework
   1. Research Objective
   2. Product Overview
   3. Market Segmentation
2. Research Methodology
   1. Qualitative Research
      1. Primary & Secondary Research
   2. Quantitative Research
   3. Market Breakdown & Data Triangulation
      1. Secondary Research
      2. Primary Research
   4. Breakdown of Primary Research Respondents, By Region
   5. Assumption & Limitation
3. Executive Summary
4. Global Orthobiologics Market Insights
   1. Industry Value Chain Analysis
   2. DROC Analysis
      1. Growth Drivers
      2. Restraints
      3. Opportunities
      4. Challenges
   3. Technological Landscape/Recent Development
   4. Regulatory Framework
   5. Porter’s Five Forces Analysis
      1. Bargaining Power of Suppliers
      2. Bargaining Power of Buyers
      3. Threat of New Entrants
      4. Threat of Substitutes
      5. Intensity of Rivalry
5. Global Orthobiologics Market Overview
   1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
   2. Market Share & Forecast
      1. By Product
         1. Demineralized Bone Matrix (DBM)
         2. Allograft
         3. Bone Morphogenetic Protein (BMP)
         4. Viscosupplementation Products
         5. Synthetic Bone Substitutes
         6. Others
      2. By Application
         1. Osteoarthritis & Degenerative Arthritis
         2. Spinal Fusion
         3. Fracture Recovery
         4. Soft Tissue Injuries
         5. Maxillofacial & Dental Applications
      3. By End User
         1. Hospitals & Ambulatory Centers
         2. Research & Academic Institute
         3. Dental Clinics
      4. By Region
         1. North America
         2. Europe
         3. The Asia Pacific
         4. Latin America
         5. The Middle East and Africa
6. North America Orthobiologics Market
   1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
   2. Market Share & Forecast
      1. By Product
      2. By Type
      3. By Application
      4. By End User
      5. By Country
         1. United States
         2. Canada
7. Europe Orthobiologics Market
   1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
   2. Market Share & Forecast
      1. By Product
      2. By Type
      3. By Application
      4. By End User
      5. By Country
         1. Germany
         2. United Kingdom
         3. Italy
         4. France
         5. Spain
         6. Rest of Europe
8. The Asia Pacific Orthobiologics Market
   1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
   2. Market Share & Forecast
      1. By Product
      2. By Type
      3. By Application
      4. By End User
      5. By Country
         1. China
         2. India
         3. Japan
         4. South Korea
         5. Rest of Asia Pacific
9. Latin America Orthobiologics Market
   1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
   2. Market Share & Forecast
      1. By Product
      2. By Type
      3. By Application
      4. By End User
      5. By Country
         1. Brazil
         2. Mexico
         3. Rest of Latin America
10. The Middle East & Africa Orthobiologics Market
    1. Market Size & Forecast by Value, 2018-2028
       1. By Value (USD Million)
    2. Market Share & Forecast
    3. By Product
    4. By Type
    5. By Application
       1. By End User
       2. By Country
          1. Saudi Arabia
          2. UAE
          3. South Africa
          4. Rest of Middle East & Africa
11. Competitive Landscape
    1. List of Key Players and Their Offerings
    2. Market Share Analysis, 2021
    3. Competitive Benchmarking, By Operating Parameters
    4. Key Strategic Development (Merger, Acquisition, Partnership.)
12. Impact of Covid-19 on Global Orthobiologics Market Industry
13. Company Profile (Company Overview, Financial Matrix, Competitive landscape, Key Personnel, Key Competitors, Contact Address, and Strategic Outlook) **
    1. Arthrex Inc.
    2. Seaspine Holdings Corporation
    3. Sanofi
    4. Bone Support
    5. DePuy Synthes
    6. Integra Lifesciences
    7. Globus Medical Inc.
    8. NuVasive Inc.
    9. Terumo Corporation
    10. Medtronic PLC
    11. Stryker Corporation
    12. Zimmer Biomet
    13. Pioneer Surgical Technology
    14. Smith & Nephew plc
    15. Bioventus LLC
    16. Orthofix, Inc.
    17. Genzyme
    18. Bone Biologics, Corp.
    19. Osiris Therapeutics, Inc.
    20. Other prominent players

14. Key Strategic Recommendations

*Financial information in case of non-listed companies will be provided as per availability

**The segmentation and the companies are subjected to modifications based on in-depth secondary for the final deliverable

List of Figures

Figure 1        Global Orthobiologics Market Segmentation

Figure 2        Global Orthobiologics Market Value Chain Analysis

Figure 3        Company Market Share Analysis, 2021

Figure 4        Global Orthobiologics Market Size, By Value (USD Million), 2018-2028

Figure 5        Global Orthobiologics Market Share, By Product, By Value, 2018-2028

Figure 6        Global Orthobiologics Market Share, By Type, By Value, 2018-2028

Figure 7        Global Orthobiologics Market Share, By Application, By Value, 2018-2028

Figure 8        Global Orthobiologics Market Share, By End User, By Value, 2018-2028

Figure 9        Global Orthobiologics Market Share, By Region, By Value, 2018-2028

Figure 10       North America Orthobiologics Market Size, By Value (USD Million), 2018-2028

Figure 11       North America Orthobiologics Market Share, By Product, By Value, 2018-2028

Figure 12       North America Orthobiologics Market Share, By Type, By Value, 2018-2028

Figure 13       North America Orthobiologics Market Share, By Application, By Value, 2018-2028

Figure 14       North America Orthobiologics Market Share, By End User, By Value, 2018-2028

Figure 15       North America Orthobiologics Market Share, By Country, By Value, 2018-2028

Figure 16       Europe Orthobiologics Market Size, By Value (USD Million), 2018-2028

Figure 17       Europe Orthobiologics Market Share, By Product, By Value, 2018-2028

Figure 18       Europe Orthobiologics Market Share, By Type, By Value, 2018-2028

Figure 19       Europe Orthobiologics Market Share, By Application, By Value, 2018-2028

Figure 20       Europe Orthobiologics Market Share, By End User, By Value, 2018-2028

Figure 21       Europe Orthobiologics Market Share, By Country, By Value, 2018-2028

Figure 22       The Asia-Pacific Orthobiologics Market Size, By Value (USD Million), 2018-2028

Figure 23       The Asia-Pacific Orthobiologics Market Share, By Product, By Value, 2018-2028

Figure 24       The Asia-Pacific Orthobiologics Market Share, By Type, By Value, 2018-2028

Figure 25       The Asia-Pacific Orthobiologics Market Share, By Application, By Value, 2018-2028

Figure 26       The Asia-Pacific Orthobiologics Market Share, By End User, By Value, 2018-2028

Figure 27       The Asia-Pacific Orthobiologics Market Share, By Country, By Value, 2018-2028

Figure 28       Latin America Orthobiologics Market Size, By Value (USD Million), 2018-2028

Figure 29       Latin America Orthobiologics Market Share, By Product, By Value, 2018-2028

Figure 30       Latin America Orthobiologics Market Share, By Type, By Value, 2018-2028

Figure 31       Latin America Orthobiologics Market Share, By Application, By Value, 2018-2028

Figure 32       Latin America Orthobiologics Market Share, By End User, By Value, 2018-2028

Figure 33       Latin America Orthobiologics Market Share, By Country, By Value, 2018-2028

Figure 34       The Middle East & Africa Orthobiologics Market Size, By Value (USD Million), 2018-2028

Figure 35       The Middle East & Africa Orthobiologics Market Share, By Product, By Value, 2018-2028

Figure 36       The Middle East & Africa Orthobiologics Market Share, By Type, By Value, 2018-2028

Figure 37       The Middle East & Africa Orthobiologics Market Share, By Application, By Value, 2018-2028

Figure 38       The Middle East & Africa Orthobiologics Market Share, By End User, By Value, 2018-2028

Figure 39       The Middle East & Africa Orthobiologics Market Share, By Country, By Value, 2018-2028

List of Tables

Table 1         Global Orthobiologics Market Size, By Product, By Value, 2018-2028                                           

Table 2         Global Orthobiologics Market Size, By Type, By Value, 2018-2028                                              

Table 3         Global Orthobiologics Market Size, By Application, By Value, 2018-2028                                                

Table 4         Global Orthobiologics Market Size, By End User, By Value, 2018-2028                                        

Table 5         Global Orthobiologics Market Size, By Region, By Value, 2018-2028                                           

Table 6         North America Orthobiologics Market Size, By Product, By Value, 2018-2028                                         

Table 7         North America Orthobiologics Market Size, By Type, By Value, 2018-2028                                             

Table 8         North America Orthobiologics Market Size, By Application, By Value, 2018-2028                                              

Table 9         North America Orthobiologics Market Size, By End User, By Value, 2018-2028                                       

Table 10        North America Orthobiologics Market Size, By Country, By Value, 2018-2028                                         

Table 11        Europe Orthobiologics Market Size, By Product, By Value, 2018-2028                                         

Table 12        Europe Orthobiologics Market Size, By Type, By Value, 2018-2028                                             

Table 13        Europe Orthobiologics Market Size, By Application, By Value, 2018-2028                                               

Table 14        Europe Orthobiologics Market Size, By End User, By Value, 2018-2028                                       

Table 15        Europe Orthobiologics Market Size, By Country, By Value, 2018-2028                                         

Table 16        The Asia-Pacific Orthobiologics Market Size, By Product, By Value, 2018-2028                                        

Table 17        The Asia-Pacific Orthobiologics Market Size, By Type, By Value, 2018-2028                                           

Table 18        The Asia-Pacific Orthobiologics Market Size, By Application, By Value, 2018-2028                                            

Table 19        The Asia-Pacific Orthobiologics Market Size, By End User, By Value, 2018-2028                                                

Table 20        The Asia-Pacific Orthobiologics Market Size, By Country, By Value, 2018-2028                                       

Table 21        Latin America Orthobiologics Market Size, By Product, By Value, 2018-2028                                          

Table 22        Latin America Orthobiologics Market Size, By Type, By Value, 2018-2028                                              

Table 23        Latin America Orthobiologics Market Size, By Application, By Value, 2018-2028                                               

Table 24        Latin America Orthobiologics Market Size, By End User, By Value, 2018-2028                                        

Table 25        Latin America Orthobiologics Market Size, By Country, By Value, 2018-2028                                          

Table 26        The Middle East & Africa Orthobiologics Market Size, By Product, By Value, 2018-2028                                               

Table 27        The Middle East & Africa Orthobiologics Market Size, By Type, By Value, 2018-2028                                         

Table 28        The Middle East & Africa Orthobiologics Market Size, By Application, By Value, 2018-2028                                               

Table 29        The Middle East & Africa Orthobiologics Market Size, By End User, By Value, 2018-2028                                               

Table 30        The Middle East & Africa Orthobiologics Market Size, By Country, By Value, 2018-2028                                               

Table 31        Arthrex Inc. Company Overview              

Table 32        Arthrex Inc. Financial Overview               

Table 33        Seaspine Holdings Corporation Company Overview                 

Table 34        Seaspine Holdings Corporation Financial Overview                  

Table 35        Sanofi Company Overview            

Table 36        Sanofi Financial Overview             

Table 37        Bone Support Company Overview           

Table 38        Bone Support Financial Overview            

Table 39        DePuy Synthes Company Overview         

Table 40        DePuy Synthes Financial Overview          

Table 41        Integra Lifesciences Company Overview             

Table 42        Integra Lifesciences Financial Overview              

Table 43        NuVasive Inc. Company Overview           

Table 44        NuVasive Inc. Financial Overview            

Table 45        Globus Medical Inc. Company Overview             

Table 46        Globus Medical Inc. Financial Overview              

Table 47        Terumo Corporation Company Overview            

Table 48        Terumo Corporation Financial Overview             

Table 49        Medtronic PLC Company Overview           

Table 50        Medtronic PLC Financial Overview  

Table 51        Stryker Corporation Company Overview             

Table 52        Stryker Corporation Financial Overview    

Table 53        Zimmer Biomet Company Overview         

Table 54        Zimmer Biomet Financial Overview

Table 55        Pioneer Surgical Technology Company Overview           

Table 56        Pioneer Surgical Technology Financial Overview  

Table 57        Smith & Nephew plc Company Overview            

Table 58        Smith & Nephew plc Financial Overview   

Table 59        Bioventus LLC Company Overview           

Table 60        Bioventus LLC Financial Overview  

Table 61        Orthofix Company Overview         

Table 62        Orthofix Financial Overview 

Table 63        Genzyme Company Overview                 

Table 64        Genzyme Financial Overview                   

Table 65        Bone Biologics, Corp. Company Overview           

Table 66        Bone Biologics, Corp. Financial Overview            

Table 67        Osiris Therapeutics Company Overview              

Table 68        Osiris Therapeutics Financial Overview