Report Overview

Global Intraoperative Radiation Therapy Market - Industry Trends & Forecast Report 2028

The global intraoperative radiation therapy market is anticipated to grow at a CAGR of 6.5% during the forecast period.  The rapid expansion of the market is predominantly due to the increased incidence of cancer, advancement of technologies, and benefits provided by IORT over traditional radiotherapy.  Additionally, expanding clinical trials investigating the use of IORT for various cancer applications are anticipated to provide the lucrative potential for market participants.

Intraoperative Radiation Therapy Market - Overview

In intraoperative radiation therapy (IORT), ionizing radiation is delivered to a particular area of the body all at once during surgery to treat cancer.  In comparison to conventional radiation therapy, IORT enables higher therapeutic doses of radiation to the tumor/tumor bed with less exposure to the healthy tissues around the tumor.  In most solid tumors, surgery is traditionally followed by external beam radiation (EBRT) or chemotherapy to eradicate any remaining microscopic disease and lower the chance of local recurrence.  The application of electron radiation directly to the remaining tumor or tumor bed during cancer surgery is known as intraoperative electron radiation therapy (IOERT) or electron intraoperative radiation therapy.  For intraoperative radiation therapy, electron beams are advantageous, as depending on the electron energy, the dose gradually decreases away from the target region, protecting healthy tissue beneath.

Global Intraoperative Radiation Therapy Market Forecast and Trends

Growth Drivers

The Rising Incidence of Cancer Cases Will Fuel Market Expansion

Over the forecast period, the market is anticipated to expand due to the rising incidence of cancers such as breast and lung cancer.  According to the World Health Organization, cancer is a primary cause of death worldwide, responsible for nearly 10 million deaths in 2020. 400,000 children are diagnosed with cancer each year.  Different nations have different most prevalent malignancies; the most prevalent form of cancer is cervical in 23 nations.  In the upcoming years, the market expansion is predicted to be aided by the rise in the number of people concerned with a higher standard of living.  As per breastcancer.org, in the United States, women are anticipated to receive diagnoses for 287,850 new instances of invasive breast cancer and 51,400 new cases of non-invasive (in situ) breast cancer in 2022.  Direct radiation to the target area is possible with IORT while normal surrounding tissue is spared.  When it is thought that minute amounts of cancer may still be present after surgery or when the cancer is hard to remove, IORT is utilized to treat the condition, and this use of IORT in the treatment of cancer is anticipated to boost the market in upcoming years.

Increasing Focus on IORT Clinical Trial for Range of Cancer Applications Will Provide Boost To The Market

Over time, IORT has been effectively used as a breast-conserving technique.  A significant number of manufacturers and research institutions are working together more frequently to perform clinical trials to examine the applicability and efficacy of IORT for additional cancer types due to technological developments in this area combined with the expanding uses of IORT.  These clinical trials main objective is to assess the viability of IORT therapy in a range of cancer applications.  The expansion of applications of intraoperative radiation therapy will boost the market over the forecast period.  For instance, in December 2021 (at Providence Saint John's Health Center In Santa Monica, California), a patient with recurrent glioblastoma (GBM) was treated with the Xoft Axxent Electronic Brachytherapy (eBx) System by iCAD, Inc., a leader in global medical technology that offers cutting-edge cancer detection and therapy solutions.

Restraints

The Lack of Qualified Oncologists Expected to Hamper Market Growth in Upcoming Years

Maximum tumor control and minimum danger to normal tissue at each stage of the process require a high degree of precision.  Interconnectivity issues between various therapeutic planning, delivery, and monitoring systems might result in procedural errors, which raises patient risks.  Due to the lack of highly qualified and experienced oncologists, these inherent IORT complications present a challenge to its wider adoption in cancer treatment.  In the event of unintentional radiation exposure, the high doses associated with therapeutic exposures tend to harm not only the patients seeking treatment but also the medical staff and anyone in the immediate vicinity.  There could be several negative effects, including nausea, vomiting, and diarrhea.  These aforementioned problems may occur due to the shortage of well-trained and skilled healthcare workers, which is expected to hamper the market growth in the upcoming years.

Impact of COVID-19 on Global Intraoperative Radiation Therapy Market

The global concern for the population's safety has increased due to the COVID-19 pandemic, which has led to the lockout situation.  Respiratory equipments were required to meet the increased demand for the recovery of the virus-exposed patients to provide better care.  The use of these gadgets is increasing on a global scale, and the makers are capitalizing on this trend to increase their market share.  However, the surgical procedures have been stopped, which will cause the other medical equipment and supplies to fail.  In order to protect hospital infrastructure for the care of COVID-19 patients, the Centers for Disease Control and a number of medical professional groups recommended delaying cancer screening and other health prevention treatments unless the risks outweighed the benefits.  In the current circumstances, this has also contributed to a decline in the intraoperative radiation therapy market expansion.  However, despite implementing measures like social distancing and total or partial lockdowns of cities, provinces, or nations, the market for intraoperative radiation therapy is gaining momentum post-COVID.

Global Intraoperative Radiation Therapy Market - By Technology

Based on technology, intraoperative radiation therapy is divided into intraoperative brachytherapy, electron intraoperative radiation therapy, and others.  In the intraoperative radiation treatment market, the electron IORT segment is anticipated to develop at the fastest rate.  This market's expansion can be ascribed to a host of advantages, such as shorter treatment times, improved depth of penetration, and homogeneous doses that work best.  Electron intraoperative radiation therapy delivers electron radiation directly to the underlying tumor or tumor bed during cancer surgery.  As the dose quickly decreases after the target site based on the electron energy, forgiving underlying healthy tissue, electron beams are excellent for intraoperative radiation therapy.  One benefit of IORT is that it is administered during the surgical procedure when tiny remaining tumor cells are most susceptible to being eliminated.  Additionally, IORT is frequently combined with external beam radiotherapy (EBRT) to speed up the healing process and use fewer doses of radiation.

Global Intraoperative Radiation Therapy Market - By Product and Service

Based on the product and service, the product segment is further segmented into applicators & afterloaders, and treatment planning systems.  It is anticipated that the products category held the largest market share in 2021.  The increased market share in this sector can be due to their expanding availability, the advancement of technologically sophisticated mobile systems and accelerators, treatment planning, and the expanding use of IORT products in treating cancer.

Global Intraoperative Radiation Therapy Market - By Application

Based on application, the intraoperative radiation therapy market is segmented into breast cancer, brain tumor, lung cancer, gastrointestinal cancer, endometrial & cervical cancer, and others.  During the anticipated period, the market for intraoperative radiation therapy is anticipated to be dominated by the breast cancer application segment.  As of 2021, breast cancer cases accounted for 12% of all new cancer cases annually, making it the most prevalent cancer globally.  The non-invasive nature of radiotherapy, the increase in breast cancer cases, and the high success rates with IORT are the main causes of this.  Lung and gastrointestinal cancer also hold a significant share in the industry.

Global Intraoperative Radiation Therapy Market - Regional Insights

The global intraoperative radiation therapy market has been segmented into North America, Europe, Asia-Pacific, Latin America, the Middle East, and Africa.  The market for intraoperative radiation therapy was dominated by North America, which is comprised of the US and Canada.  The easy accessibility and widespread adoption of IORT for cancer therapy, the rising cancer incidence, and the sizeable annual per capita healthcare spending in the US and Canada are the key factors propelling market expansion in this region.  The use of low-energy IORT has been encouraged by organizations like the American Society for Radiation Oncology (ASTRO), which has increased its penetration in North America.  Furthermore, the rising rate of lung cancer in the region, the existence of important market participants, and the introduction of new services are other factors that impact market growth across the region.

Competitive Landscape

Key players operating in the global intraoperative radiation therapy market are IntraOp Medical Corporation, GMV Innovating Solutions, ZEISS Group, iCAD Inc., Sensus Healtcare Inc., Variant Medical Systems Inc., Ariane Medical Systems,  Sordina IORT Technologies, Eckert and Ziegler Group, Elekta AB, Moffitt Cancer Center, Xoft, E-tech Industry, Derma Optic, and Electronic Technique Co, Merit Medical Systems, Dickinson and Company, RaySearch Laboratories, Salutaris Medical Devices, and other prominent players.  The market leaders retain their supremacy by spending on research and development, incorporating cutting-edge technology into their goods, and releasing upgraded items for customers.  Various tactics are used, including strategic alliances, agreements, mergers, and partnerships.

Recent Development

• In March 2022, Zeiss Medical Technology introduced the Intrabeam 600 device to provide Intraoperative Radiation Therapy (IORT) in India.  The device provides patients with early-stage breast cancer with the least intrusive therapy option.
• In July 2022, A prototype diamond-based Schottky diode detector was successfully employed by a European research team to commission an ElectronFlash research accelerator for conventional and pre-clinical FLASH radiotherapy.

Scope of the Report

By Technology

• Intraoperative Brachytherapy
• Electron Intraoperative Radiation Therapy
• Others

By Product and Service

• Products
• Applicators & Afterloaders
• Treatment and Planning Systems
• Others
• Services

By Application

• Breast Cancer
• Brain Tumor
• Lung Cancer
• Gastrointestinal Cancer
• Endometrial & Cervical Cancer
• Others

By End Users

• Hospitals
• Ambulatory Surgical Centers
• Others

By Region

• North America
• Europe
• Asia Pacific
• Latin America
• Middle East and Africa

1. Research Framework
   1. Research Objective
   2. Product Overview
   3. Market Segmentation
2. Research Methodology
   1. Qualitative Research
      1. Primary & Secondary Research
   2. Quantitative Research
   3. Market Breakdown & Data Triangulation
      1. Secondary Research
      2. Primary Research
   4. Breakdown of Primary Research Respondents, By Region
   5. Assumption & Limitation
3. Executive Summary
4. Global Intraoperative Radiation Therapy Market Insights
   1. Industry Value Chain Analysis
   2. DROC Analysis
      1. Growth Drivers
      2. Restraints
      3. Opportunities
      4. Challenges
   3. Technological Advancement/Recent Development
   4. Regulatory Framework
   5. Porter’s Five Forces Analysis
      1. Bargaining Power of Suppliers
      2. Bargaining Power of Buyers
      3. Threat of New Entrants
      4. Threat of Substitutes
      5. Intensity of Rivalry
5. Global Intraoperative Radiation Therapy Market Overview
   1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
   2. Market Share & Forecast
      1. By Technology
         1. Intraoperative Brachytherapy
         2. Electron Intraoperative Radiation Therapy
         3. Others
      2. By Product and Service
         1. Products
            1. Applicators & Afterloaders
            2. Treatment Planning Systems
         2. Services
      3. By Application
         1. Breast Cancer
         2. Brain Tumor
         3. Lung Cancer
         4. Gastrointestinal Cancer
         5. Endometrial & Cervical Cancer
         6. Others
      4. By End Users
         1. Hospitals
         2. Ambulatory Surgical Centers
         3. Others
      5. By Region
         1. North America
         2. Europe
         3. The Asia Pacific
         4. Latin America
         5. The Middle East and Africa
6. North America Intraoperative Radiation Therapy Market
   1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
   2. Market Share & Forecast
      1. By Technology
      2. By Product and Service
      3. By Application
      4. By End Users
      5. By Country
         1. United States
         2. Canada
7. Europe Intraoperative Radiation Therapy Market
   1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
   2. Market Share & Forecast
      1. By Technology
      2. By Product and Service
      3. By Application
      4. By End User
      5. By Country
         1. Germany
         2. United Kingdom
         3. Italy
         4. France
         5. Spain
         6. Rest of Europe
8. The Asia Pacific Intraoperative Radiation Therapy Market
   1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
   2. Market Share & Forecast
      1. By Technology
      2. By Product and Service
      3. By Application
      4. By End User
      5. By Country
         1. China
         2. India
         3. Japan
         4. South Korea
         5. Rest of Asia Pacific
9. Latin America Intraoperative Radiation Therapy Market
   1. Market Size & Forecast by Value, 2018-2028
      1. By Value (USD Million)
   2. Market Share & Forecast
      1. By Technology
      2. By Product and Service
      3. By Application
      4. By End User
      5. By Country
         1. Brazil
         2. Mexico
         3. Rest of Latin America
10. The Middle East & Africa Intraoperative Radiation Therapy Market
    1. Market Size & Forecast by Value, 2018-2028
       1. By Value (USD Million)
    2. Market Share & Forecast
       1. By Technology
       2. By Product and Service
       3. By Application
       4. By End User
       5. By Country
          1. Saudi Arabia
          2. UAE
          3. South Africa
          4. Rest of Middle East & Africa
11. Competitive Landscape
    1. List of Key Players and Their Offerings
    2. Market Share Analysis, 2021
    3. Competitive Benchmarking, By Operating Parameters
    4. Key Strategic Development (Merger, Acquisition, Partnership.)
12. Impact of Covid-19 on Global Intraoperative Radiation Therapy  Industry
13. Company Profile (Company Overview, Financial Matrix, Competitive landscape, Key Personnel, Key Competitors, Contact Address, and Strategic Outlook) **
    1. IntraOp Medical Corporation
    2. GMV Innovating Solutions
    3. ZEISS Group
    4. iCAD Inc.
    5. Sensus Healtcare Inc.
    6. Variant Medical Systems Inc.
    7. Ariane Medical Systems
    8. Sordina IORT Technologies
    9. Eckert and Ziegler Group
    10. Elekta AB
    11. Moffitt Cancer Center
    12. Xoft
    13. E-tech Industry
    14. Derma Optic and Electronic Technique Co
    15. Merit Medical Systems
    16. Dickinson and Company
    17. RaySearch Laboratories
    18. Salutaris Medical Devices
    19. Other prominent players

14. Key Strategic Recommendations

*Financial information in case of non-listed companies will be provided as per availability

**The segmentation and the companies are subjected to modifications based on in-depth secondary for the final deliverable

List Of Figures

Figure 1        Global Intraoperative Radiation Therapy Segmentation

Figure 2        Global Intraoperative Radiation Therapy Market Value Chain Analysis

Figure 3        Company Market Share Analysis, 2021

Figure 4        Global Intraoperative Radiation Therapy Market Size, By Value (USD Million), 2018-2028

Figure 5        Global Intraoperative Radiation Therapy Market Share, By Technology, By Value, 2018-2028

Figure 6        Global Intraoperative Radiation Therapy Market Share, By Product and Service, By Value, 2018-2028

Figure 7        Global Intraoperative Radiation Therapy Market Share, By Application, By Value, 2018-2028

Figure 8        Global Intraoperative Radiation Therapy Market Share, By End User, By Value, 2018-2028

Figure 9        Global Intraoperative Radiation Therapy Market Share, By Region, By Value, 2018-2028

Figure 10       North America Intraoperative Radiation Therapy Market Size, By Value (USD Million), 2018-2028

Figure 11       North America Intraoperative Radiation Therapy Market Share, By Technology, By Value, 2018-2028

Figure 12       North America Intraoperative Radiation Therapy Market Share, By Product and Service, By Value, 2018-2028

Figure 13       North America Intraoperative Radiation Therapy Market Share, By Application, By Value, 2018-2028

Figure 14       North America Intraoperative Radiation Therapy Market Share, By End User, By Value, 2018-2028

Figure 15       North America Intraoperative Radiation Therapy Market Share, By Country, By Value, 2018-2028

Figure 16       Europe Intraoperative Radiation Therapy Market Size, By Value (USD Million), 2018-2028

Figure 17       Europe Intraoperative Radiation Therapy Market Share, By Technology, By Value, 2018-2028

Figure 18       Europe Intraoperative Radiation Therapy Market Share, By Product and Service, By Value, 2018-2028

Figure 19       Europe Intraoperative Radiation Therapy Market Share, By Application, By Value, 2018-2028

Figure 20       Europe Intraoperative Radiation Therapy Market Share, By End User, By Value, 2018-2028

Figure 21       Europe Intraoperative Radiation Therapy Market Share, By Country, By Value, 2018-2028

Figure 22       The Asia-Pacific Intraoperative Radiation Therapy Market Size, By Value (USD Million), 2018-2028

Figure 23       The Asia-Pacific Intraoperative Radiation Therapy Market Share, By Technology, By Value, 2018-2028

Figure 24       The Asia-Pacific Intraoperative Radiation Therapy Market Share, By Product and Service, By Value, 2018-2028

Figure 25       The Asia-Pacific Intraoperative Radiation Therapy Market Share, By Application, By Value, 2018-2028

Figure 26       The Asia-Pacific Intraoperative Radiation Therapy Market Share, By End User, By Value, 2018-2028

Figure 27       The Asia-Pacific Intraoperative Radiation Therapy Market Share, By Country, By Value, 2018-2028

Figure 28       Latin America Intraoperative Radiation Therapy Market Size, By Value (USD Million), 2018-2028

Figure 29       Latin America Intraoperative Radiation Therapy Market Share, By Technology, By Value, 2018-2028

Figure 30       Latin America Intraoperative Radiation Therapy Market Share, By Product and Service, By Value, 2018-2028

Figure 31       Latin America Intraoperative Radiation Therapy Market Share, By Application, By Value, 2018-2028

Figure 32       Latin America Intraoperative Radiation Therapy Market Share, By End User, By Value, 2018-2028

Figure 33       Latin America Intraoperative Radiation Therapy Market Share, By Country, By Value, 2018-2028

Figure 34       The Middle East & Africa Intraoperative Radiation Therapy Market Size, By Value (USD Million), 2018-2028

Figure 35       The Middle East & Africa Intraoperative Radiation Therapy Market Share, By Technology, By Value, 2018-2028

Figure 36       The Middle East & Africa Intraoperative Radiation Therapy Market Share, By Product and Service, By Value, 2018-2028

Figure 37       The Middle East & Africa Intraoperative Radiation Therapy Market Share, By Application, By Value, 2018-2028

Figure 38       The Middle East & Africa Intraoperative Radiation Therapy Market Share, By End User, By Value, 2018-2028

Figure 39       The Middle East & Africa Intraoperative Radiation Therapy Market Share, By Country, By Value, 2018-2028

List Of Tables

Table 1         Global Intraoperative Radiation Therapy Market Size, By Technology, By Value, 2018-2028

Table 2         Global Intraoperative Radiation Therapy Market Size, By Product and Service, By Value, 2018-2028

Table 3         Global Intraoperative Radiation Therapy Market Size, By Application, By Value, 2018-2028

Table 4         Global Intraoperative Radiation Therapy Market Size, By End User, By Value, 2018-2028

Table 5         Global Intraoperative Radiation Therapy Market Size, By Region, By Value, 2018-2028

Table 6         North America Intraoperative Radiation Therapy Market Size, By Technology, By Value, 2018-2028

Table 7         North America Intraoperative Radiation Therapy Market Size, By Product and Service, By Value, 2018-2028

Table 8         North America Intraoperative Radiation Therapy Market Size, By Application, By Value, 2018-2028

Table 9         North America Intraoperative Radiation Therapy Market Size, By End User, By Value, 2018-2028

Table 10        North America Intraoperative Radiation Therapy Market Size, By Country, By Value, 2018-2028

Table 11        Europe Intraoperative Radiation Therapy Market Size, By Technology, By Value, 2018-2028

Table 12        Europe Intraoperative Radiation Therapy Market Size, By Product and Service, By Value, 2018-2028

Table 13        Europe Intraoperative Radiation Therapy Market Size, By Application, By Value, 2018-2028

Table 14        Europe Intraoperative Radiation Therapy Market Size, By End User, By Value, 2018-2028

Table 15        Europe Intraoperative Radiation Therapy Market Size, By Country, By Value, 2018-2028

Table 16        The Asia-Pacific Intraoperative Radiation Therapy Market Size, By Technology, By Value, 2018-2028

Table 17        The Asia-Pacific Intraoperative Radiation Therapy Market Size, By Product and Service, By Value, 2018-2028

Table 18        The Asia-Pacific Intraoperative Radiation Therapy Market Size, By Application, By Value, 2018-2028

Table 19        The Asia-Pacific Intraoperative Radiation Therapy Market Size, By End User, By Value, 2018-2028

Table 20        The Asia-Pacific Intraoperative Radiation Therapy Market Size, By Country, By Value, 2018-2028

Table 21        Latin America Intraoperative Radiation Therapy Market Size, By Technology, By Value, 2018-2028

Table 22        Latin America Intraoperative Radiation Therapy Market Size, By Product and Service, By Value, 2018-2028

Table 23        Latin America Intraoperative Radiation Therapy Market Size, By Application, By Value, 2018-2028

Table 24        Latin America Intraoperative Radiation Therapy Market Size, By End User, By Value, 2018-2028

Table 25        Latin America Intraoperative Radiation Therapy Market Size, By Country, By Value, 2018-2028

Table 26        The Middle East & Africa Intraoperative Radiation Therapy Market Size, By Technology, By Value, 2018-2028

Table 27        The Middle East & Africa Intraoperative Radiation Therapy Market Size, By Product and Service, By Value, 2018-2028

Table 28        The Middle East & Africa Intraoperative Radiation Therapy Market Size, By Application, By Value, 2018-2028

Table 29        The Middle East & Africa Intraoperative Radiation Therapy Market Size, By End User, By Value, 2018-2028

Table 30        The Middle East & Africa Intraoperative Radiation Therapy Market Size, By Country, By Value, 2018-2028

Table 31        IntraOp Medical Corporation Company Overview

Table 32        IntraOp Medical Corporation Financial Overview

Table 33        GMV Innovating Solutions Company Overview

Table 34        GMV Innovating Solutions Financial Overview

Table 35        ZEISS Group Company Overview

Table 36        ZEISS Group Financial Overview

Table 37        iCAD Inc.  Company Overview

Table 38        iCAD Inc.  Financial Overview

Table 39        Sensus Healtcare Inc. Company Overview

Table 40        Sensus Healtcare Inc. Financial Overview

Table 41        Variant Medical Systems Inc. Company Overview

Table 42        Variant Medical Systems Inc. Financial Overview

Table 43        Ariane Medical Systems Company Overview

Table 44        Ariane Medical Systems Financial Overview

Table 45        Sordina IORT Technologies Company Overview

Table 46        Sordina IORT Technologies Financial Overview

Table 47        Eckert and Ziegler Group Company Overview

Table 48        Eckert and Ziegler Group Financial Overview

Table 49        Elekta AB Company Overview

Table 50        Elekta AB Financial Overview

Table 51        Moffitt Cancer Center Company Overview

Table 52        Moffitt Cancer Center Financial Overview

Table 53        Merit Medical Systems Company Overview

Table 54        Merit Medical Systems Financial Overview

Table 55        Dickinson and Company Overview

Table 56        Dickinson and Company Financial Overview

Table 57        RaySearch Laboratories Company Overview

Table 58        RaySearch Laboratories Financial Overview

Table 59        Salutaris Medical Devices Company Overview

Table 60        Salutaris Medical Devices Financial Overview